Efecto de la administración oral continuada de Boldoa purpurascens Cav. sobre diferentes variables fisiológicas en ratas (Effect of the continuing oral administration of Boldoa purpurascens Cav. on different physiological variables in rats)

A study was conducted to verify the diuretic effect of the aqueous extract of Boldoa purpurascens Cav. And evaluate the different physiological variables upon continued implementation (14 days). 5 rats were used S / D to check the diuretic effect of the raw material and 40 rats in the same line for the continuous dose evaluation. There was a great diuretic activity of the plant at a dose of 400 mg / kg. During clinical evaluations no abnormalities were observed in the behavior of the animals studied. There were statistical differences in the values of hemoglobin, hematocrit, glucose, sodium and potassium, being highly significant in the three last parameters. The administration of the plant presents diuretic effect to the dose studied, its continued administration decreases significantly Hb values and hematocrit, affecting mostly potassium homeostasis and decreases the glucose at 14 days.