The association between pneumococcal vaccination, ethnicity, and the nasopharyngeal microbiota of children in Fiji
2019
Background
Streptococcus pneumoniae is a significant global pathogen that colonises the nasopharynx of healthy children. Pneumococcal conjugate vaccines, which reduce nasopharyngeal colonisation of vaccine-type S. pneumoniae, may have broader effects on the nasopharyngeal microbiota; however, data are limited. In Fiji, nasopharyngeal carriage prevalence of S. pneumoniae and other colonising species differ between the two main ethnic groups. Here, we examined the association between the 7-valent pneumococcal conjugate vaccine (PCV7) and the nasopharyngeal microbiota of children in Fiji, including for each of the two main ethnic groups—indigenous Fijians (iTaukei) and Fijians of Indian descent (FID).
Keywords:
- Biology
- Virology
- Pneumococcal vaccination
- Pneumococcal conjugate vaccine
- Immunology
- Ethnic group
- Colonisation
- Medical microbiology
- Pneumococcal conjugate vaccination
- Carriage
- Streptococcus pneumoniae
- Pneumococcal infections
- Respiratory tract infections
- Upper respiratory tract infection
- Moraxella catarrhalis
- Haemophilus
- Haemophilus influenzae
- Medicine
- Correction
- Source
- Cite
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