Urinary excretion of sialic acid in patients with superficial bladder tumors

Urinary total sialic acid/creatinine (TSACr) ratio was determined in 73 patients with superficial bladder tumors and 34 healthy volunteers. The mean TSACr value in the tumor group was higher than the control group (P < 0.001) and this difference was significant. Comparing the urinary TSACr ratio of T1, Ta, grade I–II, grade III, single, multiple, primary and recurrent tumors, with the control group revealed significant results (P < 0.001). Therefore the urinary TSACr ratio determination in the follow-up of these patients may be used as a non-invasive procedure.