Change of fluidity of mammary epithelial cells envelope of dairy goats with mastitis

To study the change of fluidity of mammary epithelial cells envelope of dairy goats, the content of malondialdehyde (MDA) and micro-consistency (η) of mammary epithelial cells envelope of dairy goats were detected. The results showed that the content of MDA and η of mammary epithelial cells envelope in dairy goats with mastitis was significantly higher than other groups (P0.01), vaccine group was significantly lower than mastitis group(P0.01), traditional Chinese medicine group was significantly lower than control group (P0.05, P0.01), combination group was significantly lower than vaccine group(P0.01), and combination group was not significantly different with traditional Chinese medicine group (P0.05). The increasing of content of MDA and disordering of fluidity of mammary epithelial cell membrane indicated that the normal function of cellular membrane was affected in dairy goats with mastitis. Mastitis vaccine and traditional Chinese medicine could prevent free radicals to damage mammary epithelial cells membrane.