Prospective evaluation of prostate with transrectal spectral Doppler with biopsy correlation: a clinicopathologic study.

Objectives:To compare the transrectal (TR) spectral Doppler findings between benign prostatic hyperplasia group and prostate cancer group.Methods:All the patients were assessed for adequate preparation, and informed consent was obtained prior to the procedure. The control group (n = 33) comprised patients who were negative for malignancy on biopsy. The study group (n = 22) were positive for malignancy and were also divided into three groups on the basis of the Gleason score. Study parameters included mean values for resistive index (RI), pulsatality index (PI), systolic/diastolic ratio (S/D) and peak systolic velocity (PSV). These were separately measured for bilateral capsular and urethral branches and compared between groups. In patients with unilateral tumour, these were compared between the tumour and non-tumour sides. Finally, the parameters were compared with patient's age. Mann–Whitney U test was used to evaluate the statistical significance.Results:The mean values of RI, PI, S/D and PSV were found...