Chemodivergent Couplings of N-Arylureas and Methyleneoxetanones via Rh(III)-Catalyzed and Solvent-Controlled C–H Activation
2019
The efficient couplings of diverse N-arylureas and methyleneoxetanones have been realized via Rh(III)-catalyzed and solvent-controlled chemoselective C–H functionalization, which involved the tunable β-H elimination and β-O elimination processes, thereby giving divergent access to quinolin-2(1H)-ones and ortho-allylated N-arylureas with broad substrate compatibility and good functional group tolerance. the divergent synthetic utilities of the transformations have also been exemplified by subsequently tandem C–H allylation, unsymmetrical C–H functionalization, alternative reaction mode, as well as removal of the carbamoyl group.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
79
References
18
Citations
NaN
KQI