How well do caregivers detect mild cognitive change in Parkinson's disease?†

Using the Cambridge Behavior Inventory-Revised, this study evaluated the relationship between caregiver ratings of cognitive change and neuropsychological performance. In sixty-one nondemented patients with Parkinson's Disease (PD; mean age = 64.5 years, MMSE = 28.7), 62% met criteria for mild cognitive impairment. This group were rated as having more overall change as well as memory and behavior change. Caregiver ratings were related to poorer psychomotor speed, learning/memory, language, and executive functioning. The capacity for caregivers to rate mild cognitive change in PD may be useful to assist in early screening and intervention approaches. © 2010 Movement Disorder Society