A Case of Invasive Fungal Sinusitis Accompanied with Inflammatory Pseudotumor in Skull Base

Skull base osteomyelitis typically arises as a complication of ear infection in older diabetic patients, but atypical skull base osteomyelitis arising from the sphenoid or occipital bones without external otitis can occur much less frequently and initially may present headache as the only symptom. Inflammatory pseudotumor is an idiopathic condition characterized by the sclerosing inflammation, which mimicks a neoplastic process. Inflammatory pseudotumor involving skull base and cervical spine is distinctly rare and usually indistinguishable from aggressive neoplasms or infection at these area. We report a case which was confirmed histologcally as invasive fungal sinusitis accompanied with inflammatory pseudotumor：the treatment consisted of amphotericin B and systemic steroid therapy but ended in a failure. (Korean J Otolaryngol 2005;48:1173-6)