Cell surface antigen of encapsulated Staphylococcus epidermidis ATCC 31432.
1987
The cell surface antigen (CSA) from encapsulated Staphylococcus epidermidis ATCC 31432 was isolated and fractionated by DEAE-Sephadex ion-exchange chromatography. It yielded a single precipitin line against rabbit antiserum and was composed of galactose, glucosamine, and two (so far) unidentified carbohydrates linked to a protein backbone. Glycerol could not be detected. In an experimental mouse infection, CSA showed some protective activities, enhancing the stimulation of granulocytes as well as the immunoglobulin M response. Apparently, CSA is different from teichoic acid.
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