ONO-8430506: A Novel Autotaxin Inhibitor That Enhances the Antitumor Effect of Paclitaxel in a Breast Cancer Model

Yuzo Iwaki,Akira Ohhata,Shingo Nakatani,Katsuya Hisaichi,Yasuyuki Okabe,Atsushi Hiramatsu,Toshihide Watanabe,Shingo Yamamoto,Taihei Nishiyama,Juta Kobayashi,Yasuo Hirooka,Hideki Moriguchi,Tatsuo Maeda,Makoto Katoh,Yuka Komichi,Hiroto Ota,Naoya Matsumura,Masahiro Okada,Tetsuya Sugiyama,Hiroshi Saga,Akira Imagawa

ONO-8430506: A Novel Autotaxin Inhibitor That Enhances the Antitumor Effect of Paclitaxel in a Breast Cancer Model

2020

Lysophosphatidic acid (LPA) is a bioactive lipid mediator that elicits a number of biological functions, including smooth muscle contraction, cell motility, proliferation and morphological change. ...

Keywords:

Breast Cancer Model
Motility
Paclitaxel
Pharmacology
Mediator
smooth muscle contraction
Biology
Autotaxin
bioactive lipid
Lysophosphatidic acid

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