Nephrogenic fibrosing dermopathy: First Colombian case
2007
: A 67-year-old woman with acute renal insufficiency, who was on hemodialysis, developed progressive skin lesions consistent with thickening and hardening of the skin in both the back and extremities without contracture upon flexure. Her face was not affected. Laboratory evaluation was unremarkable and a skin biopsy showed an increase in collagen and interstitial mucin with no inflammatory infiltrate. These clinical features resemble a new recently reported disorder, nephrogenic fibrosing dermopathy. This disorder manifests itself as scleromyxedema-like skin lesions without associated paraproteinemia, occurring in the setting of renal disease. The incidence, prevalence and etiology of the disease are unknown and currently no effective treatment is available. This is the first case reported in Colombia.
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