HISTOMORPHEMITC EVALUATION OF THE EFFICACY OF AMNIOTIC CHORION MEMBRANE IN MANAGEMENT OF GRADE II FURCATION DEFECTS (IN VITRO STUDY)

Introduction: Treatment of furcation defects especially critical size defects remains a considerable challenge in clinical practice. Treatment modalities vary according to the type and location of the defects. Regenerative procedures are one of the treatment modalities in furcation involvement. Objectives: The aim of this study was to evaluate histomorphometrically the regenerative potential of amnion chorion membrane (ACM) on the management of induced grade II furcation defects and compare it to collagen membrane. Material and methods: This study was conducted on eight adult male Mongrel dogs, about 18-24 months old, weighing approximately 18-24 Kgs. On the left sides; the created defects were filled with β-tricalcium phosphate + hydroxy apatite and covered by amnion chorion membrane (study group). While on the right sides; the created defects were filled with the β-tricalcium phosphate + hydroxyapatite then covered by collagen membranes (control group). Results: ACM has shown superior results in bone formation when compared to control group treated with resorbable collagen membrane. Conclusion: ACM is an effective, easy to handle, safe, and time saving membrane that can be used in periodontal regeneration and management of grade II furcation defects.