Primary Amyloidosis with Gastric Involvement

Amyloidosis can involve all the segments of the gastrointestinal system (GIS) from mouth to anal canal.1 Gastric involvement may appear as a component of primary amyloidosis (AL), secondary amyloidosis (AA), dialysisdependent (β2-microglobulin) amyloidosis. Gastric involvement is seen rare in primary amyloidosis and can cause symptoms, such as upper gastrointestinal bleeding, abdominal pain, weight loss, nausea and vomiting.2-4 We present a case of amyloidosis that is detected by gastric biopsy taken in esophagogastroduodenoscopy (EGD) performed to investigate the etiology of weight loss, nausea and vomiting.