Effect of Bardoxolone Methyl on Kidney Function in Patients with T2D and Stage 3b-4 CKD

Pablo E. Pergola,Melissa Krauth,J. Warren Huff,Deborah A. Ferguson,Stacey Ruiz,Colin J. Meyer,David G. Warnock

Effect of Bardoxolone Methyl on Kidney Function in Patients with T2D and Stage 3b-4 CKD

2011

Pablo E. Pergola
Melissa Krauth
J. Warren Huff
Deborah A. Ferguson
Stacey Ruiz
Colin J. Meyer
David G. Warnock

Background/Aims: Bardoxolone methyl, a novel synthetic triterpenoid, induces Nrf2, a transcription factor known to play a key role in decreasing oxidative stress and the production

Keywords:

Renal function
Bardoxolone
Inflammation
Blood urea nitrogen
Bardoxolone methyl
Type 2 diabetes
Endocrinology
Oxidative stress
Internal medicine
Medicine
Diabetes mellitus
Transcription factor

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