Identification of a novel linear B-cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates

Li Yi,Zhigang Cao,Mingwei Tong,Yuening Cheng,Yong Yang,Shuang Li,Jianke Wang,Peng Lin,Yaru Sun,Miao Zhang,Shipeng Cheng

Identification of a novel linear B-cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates

2017

Li Yi
Zhigang Cao
Mingwei Tong
Yuening Cheng
Yong Yang
Shuang Li
Jianke Wang
Peng Lin
Yaru Sun
Miao Zhang
Shipeng Cheng

Background The Nucleoprotein (NP) is the most abundant and highly immunogenic protein in canine distemper virus (CDV), playing an important role in CDV viral replication and assembly.

Keywords:

Canine distemper
Molecular biology
Viral replication
Epitope
Virology
Biology
Nucleoprotein
Virus
Sequence analysis
Monoclonal antibody
B cell
Virulence
Linear epitope

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