Cloning of Poly(ADP-ribose) Polymerase cDNA from Lower Eukaryotes

Masanao Miwa,Youichi Ozawa,Masako Uchida,Shigeki Kushida,Yoshihiro Ami,Masayuki Matsumura,Kazuhiko Uchida

Cloning of Poly(ADP-ribose) Polymerase cDNA from Lower Eukaryotes

1992

Masanao Miwa
Youichi Ozawa
Masako Uchida
Shigeki Kushida
Yoshihiro Ami
Masayuki Matsumura
Kazuhiko Uchida

Poly(ADP-ribose) polymerase (EC 2.4.4.30) catalyzes DNA-dependent ADP-ribosylation of nuclear proteins with NAD as a substrate (1-8). Poly(ADP-ribose) polymerase activity was reported from various eukaryotic cells but not from prokaryotic cells (1-8).

Keywords:

Substrate (chemistry)
Cloning
Nuclear protein
Poly ADP ribose polymerase
Polymerase
Molecular biology
Southern blot
Complementary DNA
NAD+ kinase
Chemistry

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