Research progress of intravascular cooling in clinical treatment of heatstroke

Heatstroke is a disease with high morbidity and mortality that causes a patient's core body temperature to be higher than 40.5 ℃ and combined with organ dysfunction when human body exposed to high temperature, high humidity and slow air circulation environment or after strenuous exercise. Early diagnosis and early cooling can significantly improve patient prognosis, increase patient survival rate and reduce complications. The cooling measures include extravascular cooling which mainly refers to physical cooling of body surface and intravascular cooling is mainly for patients who are not suitable for physical cooling or whose diagnosis and treatment are delayed due to lack of resources, especially for patients with heatstroke, which has a better cooling effect and can improve the prognosis of patients. Currently, the commonly used intravascular cooling measures in clinical practice mainly include intravascular infusion cooling, intravascular temperature management devices cooling and continuous blood purification. This article reviews the classification, mechanism, clinical application, advantages and disadvantages of intravascular cooling. DOI: 10.11855/j.issn.0577-7402.2021.05.16