Synthesis method of novel compound 4,4'-bis(trimethylsilyl)-2,2'-bipyridyl

2011 
The invention belongs to the technical field of organic synthesis and particularly relates to a synthesis method of novel compound 4,4'-bis(trimethylsilyl)-2,2'-bipyridyl. According to the synthesis method, 2,2'-dipyridyl is utilized as an original raw material. The synthesis method comprises the following steps of: oxidation reaction: oxidating 2,2'-dipyridyl by utilizing an oxidizer, so as to generate a 2,2'-dipyridyl N,N'-oxide; nitration reaction: nitrating the 2,2'-dipyridyl N,N'-oxide in sulfuric acid by virtue of fuming nitric acid, so as to generate 4,4'-binitro-2,2'-dipyridyl N,N'-oxide; bromination reaction: performing bromine substitution reaction on the 4,4'-binitro-2,2'-dipyridyl N,N'-oxide in the presence of a brominating agent under an acid environment, so as to generate 4,4'-dibromo-2,2'-dipyridyl N,N'-oxide; deoxidation reaction: enabling the 4,4'-dibromo-2,2'-dipyridyl N,N'-oxide and phosphorus tribromide to react in a solvent, so as to generate 4,4'-dibromo-2,2'-dipyridyl; and trimethyl silicification reaction: enabling the 4,4'-dibromo-2,2'-dipyridyl and a trimethyl silanion solution to react, so as to obtain the 4,4'-bis(trimethylsilyl)-2,2'-bipyridyl. The synthesis method provided by invention has the advantages that the operation is simple, used materials are cheap and easily available, the yield is higher, the product purity is high, the product performance is excellent, and the method is better in development prospect and application potential.
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