Evaluation of the diagnostic value of dobutamine stress echocardiography on coronary disease by color kinesis and intelligent acoustic quantification

Objective Using color kinesis (CK) and intelligent acoustic quantification (AQi),regional wall motion abnormality (WMA) and the left ventricular function variation induced by dobutamine stress test (DST) coronary artery disease (CAD) were detected in order to make a quantification method for the early diagnosis of CAD.Methods Forty five subjects with suspected CAD underwent dobutamine stress CK and AQi echocardiograhic test (CK AQi DSE) and their results were compared with those from coronary anteriography.Results After dobutamine infusion the heart rate, systolic pressure, and rate pressure product (RPP) were increased markedly. The ejection fraction (EF) and peak filling rate (PFR) were decreased and the time of peak filling rate (TPFR) was prolonged. Meanwhile the wall motion score index was increased significantly. The sensitivity, specificity, accuray and concordance of DSE for CAD detection were 96.5 %, 93.7 %, 95.5 %, and 90.3 %, respectively.Conclusions AQi CK DSE is a realiable and quantitative method to analyse the left ventricular function and WMA of CAD.