Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France

Christophe Rodriguez,Meriadeg Ar Gouilh,Nicolas Weiss,Sébastian Ströer,Karima Mokhtari,Danielle Seilhean,Bertrand Mathon,Vanessa Démontant,Mélissa N’Debi,G. Gricourt,Paul-Louis Woerther,Jean-Michel Pawlotsky,Karl Stefic,Julien Marlet,Pierre-François Dequin,Antoine Guillon,Valérie Pourcher,David Boutolleau,Astrid Vabret,Sonia Burrel

Fatal Measles Inclusion-Body Encephalitis in Adult with Untreated AIDS, France

2020

We report a fatal case of measles inclusion-body encephalitis occurring in a woman from Romania with AIDS. After an extensive but unsuccessful diagnostic evaluation, a pan-pathogen shotgun metagenomic approach revealed a measles virus infection. We identified no mutations previously associated with neurovirulence.

Keywords:

HIV/AIDS
Measles Inclusion Body Encephalitis
Pediatrics
Medicine

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