Synthesis of 52Hydroxymethylf urf ural via Dehydration of Fructose

52Hydroxymethylfurfural ( HMF) is a kind of important monomer of biomaterials and possesses wide application value. Selective dehydration of hexose , such as D2fructose , is one of main synthetic methods for 52 hydroxymethylfurfural. This paper first systemically introduces the recent applications of different homogeneous and heterogeneous acid catalysts in this yield. Then , it reviews the recent development of different reaction solvent systems applied in this reaction , including bi2phase solvent systems , subΠsupercritical fluid solvent systems , ionic liquid solvent systems and so on. At last , it points out that the future study direction in this yield is the exploitation and improvement of new heterogeneous acid catalysts as well as highly efficient solvent systems.