Evaluation of Alfuzosin efficacy in reducing postoperative flank pain during voiding in patients with ureteric stent

Objective: To evaluate the efficacy of alfuzosin in reducing postoperative flank pain during voiding, in patients with ureteric stent. Methodology: This randomized control trial was conducted at Urology Department, Liaquat National Hospital, Karachi from April to October 2014. Participants of the study were divided into Group A receiving alfuzosin and Group B receiving placebo for 6-weeks duration. Postoperatively, stent-related flank pain during voiding was assessed at the end of the sixth week and a mean score of pain was calculated. SPSS version 21 was used to analyze data, with p≤ 0.05 taken as significant. Results: A total of 70 patients with a mean age of 33±7.67 years were enrolled in the study. Mean pain score in alfuzosin group was 3.16±1.48 and in the placebo group 5.89±1.52. Among alfuzosin group, efficacy was observed in 24 (68.57%) patients while in the placebo group, in only 5 (14.28%) patients (p