Anti-diabetic formulations of Nāga bhasma (lead calx): A brief review

Introduction: Ayurvedic formulations usually contain ingredients of herbal, mineral, metal or animal in origin. N ā ga bhasma (lead calx) is a potent metallic formulation mainly indicated in the treatment of Prameha (~diabetes). Until date, no published information is available in compiled form on the formulations containing N ā ga bhasma as an ingredient, their dose and indications. Therefore, in the present study, an attempt has been made to compile various formulations of N ā ga bhasma indicated in treating Prameha. Aim: The present work aims to collect information on various formulations of N ā ga bhasma mainly indicated in treating Prameha and to elaborate the safety and efficacy of N ā ga bhasma as a Pramehaghna (antidiabetic) drug. Materials and Methods : Critical review of formulations of N ā ga bhasma is compiled from various Ayurvedic texts and the therapeutic efficacy of N ā ga bhasma is discussed on the basis of available data. Result and Conclusion: Antidiabetic formulations of N ā ga bhasma were discovered around 12 th century CE. There are 44 formulations of N ā ga bhasma mainly indicated for Prameha . Haridr ā ( Curcuma longa Linn ), Ā malak ī ( Emblica officinalis ), Gu ḍ ū ci ( Tinospora cordifolia ) and Madhu (honey) enhance the antidiabetic action of N ā ga bhasma and also help to prevent diabetic complications as well as any untoward effects of N ā ga bhasma . On the basis of the reviewed research, it is concluded that N ā ga bhasma possesses significant antidiabetic property.