Ethanol Sensitizes the Nervous System of Caenorhabditis elegans Nematode to Heat Stress

Ethanol sensitizes the nervous system of C. elegans to heat stress, which manifested in exacerbation of locomotion disturbances induced by exposure to constant temperature 36°C. Adaptation of C. elegans to high temperature by heat shock (1 h at 32oC and 1 h at 18°C) or two-hour exposure at 30°C resulted considerably reduced sensitivity of the nervous system to the negative effects of ethanol under conditions of heat stress.