A Close Correlation of Fasting Insulin Levels to Blood Pressure in Obese Children

Many epidemiologic studies suggest that obesity is an important factor in the development of hypertension (1,2). However, the mechanism linkage of obesity to hypertension has not been fully elucidated (3,4). Especially in adult obese subjects, they have various degrees of arteriosclerosis in each case because the severity of metabolic disorders and the duration of obesity were different in each case, and it may be related with hypertension or cardiac function in obesity (5). However, it is difficult to estimate the effect of arteriosclerosis on blood pressure quantitatively. Therefore, we studied the relationship between blood pressure and obesity in school children in order to exclude the effects of aging and arteriosclerotic factors and clarify the direct effect of obesity on blood pressure in this population.