Major Metabolites of Ginseng Sapogenins formed by Rat Liver Microsomes

Ryoji Kasai,Kazumasa Hara,Rumiko Dokan,Noriko Suzuki,Tohru Mizutare,Shinichi Yoshihara,Kazuo Yamasaki

Major Metabolites of Ginseng Sapogenins formed by Rat Liver Microsomes

2000

Ryoji Kasai
Kazumasa Hara
Rumiko Dokan
Noriko Suzuki
Tohru Mizutare
Shinichi Yoshihara
Kazuo Yamasaki

Incubation of ginseng sapogenins with microsomes from rat liver resulted in formation of their 20, 24-epoxides as major metabolites. Identification of the metabolites was performed by HPLC, FAB-MS and EI-MS.

Keywords:

Microsome
Sapogenin
Ginsenoside
Protopanaxatriol
Ginseng
Protopanaxadiol
Terpenoid
Chemistry
Steroid
Biochemistry
Pharmacognosy
Araliaceae

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