Impact of the COVID-19 pandemic in houston on stroke care in a health system of 10 stroke centers

Introduction: We assessed the impact of COVID-19 pandemic on stroke admissions and care metrics within a health system of 10 stroke centers, with 4 comprehensive stroke centers (CSC) in the greater Houston region Methods: Between January-June 2019 and January-June 2020, we compared the proportion of ischemic strokes (total & direct CSC presentations) & intracerebral hemorrhage (ICH) relative to total admissions using logistic regression, and among the direct CSC presentations, we compared door to tPA and thrombectomy times using Wilcoxon Rank Sum Results: A total of 4808 cases were assessed (Table 1) There was an initial drop of ∼30% in cases at the pandemic onset (Fig 1) Numerically fewer patients in the 2020 period were seen at primary and CSCs (Table 1) Compared to 2019, there was a significant reduction in transferred patients [N(%), 829 (36) vs 637 (34), p=0 02], in hospital strokes [N(%), 111 (5) vs 69 (4), p=0 04], and mild strokes (NIHSS 1-5) [N (%), 891 (43) vs 635 (40),p=0 02], and no significant differences in the proportions of total ischemic strokes [OR (95% CI)=0 92 (0 79, 1 06), p=0 23], direct CSC presentations [OR (95% CI) =0 96 (0 86, 1 08), p=0 48] and ICH [OR (95% CI) =1 14 (0 98, 1 33), p=0 08] in 2020 (Fig 1) Among the direct ischemic strokes at CSCs, there were similar mean (SD) (mins) door to tPA [44 (17) vs 42 (17), p=0 14] but significantly prolonged door to thrombectomy times [94 (15) vs 85 (20), p=0 005] in 2020 Conclusion: COVID-19 pandemic led to reduced mild stroke admissions, transfers and in hospital stroke alerts, & prolonged door to thrombectomy times Identifying reasons to mitigate this discrepancy is crucial for next pandemic preparedness (Figure Presented)