Evaluation of the Clinical Utility of an IrisTM Collimator Combined with a Sequential Optimization Algorithm for Robotic Radiosurgery

Iris collimation and sequential beam weight optimization are two recently introduced technologies for robotic radiosurgery. We have evaluated the clinical utility of these technologies by comparing treatment plans generated using them with plans generated using fixed collimators and alternative optimization algorithms for 19 clinical cases and four optimization objectives. In every case an improved solution was obtained when using the Iris Collimator and sequential optimization, resulting in fewer total MU, better target coverage, better dose conformality, and/or better dose homogeneity. These improvements suggest that the new collimation system and optimization algorithm will have high clinical utilization.