A Case of Laryngeal Non-Hodgkin’s Lymphoma

Malignant lymphoma of the larynx is very rare with a reported incidence of less than 1% of all laryngeal malignancies. A case of laryngeal non-Hodgkin's lymphoma (diffuse large B cell type) in an 89-year-old female is reported. At the initial consultation, the patient had complained of abnormal sensation in the pharyngolaryngeal region that had persisted for a few days. Endoscopic examination demonstrated a supraglottic mass with a smooth surface. The histopathological diagnosis was diffuse large B cell lymphoma. There was no other evidence of lymphoma anywhere except a regional lymph node. The patient was diagnosed as having clinical stage IIEA and treated with 30 Gy's irradiation alone because of her poor performance status. Six months after the initial treatment, tumor recurrence occurred in the right tonsil and treated with chemoradiotherapy that was 3 courses of CHOP and 30 Gy's concurrent radiotherapy followed by 4 courses of R-CHOP. There was no recurrence observed for 8 months after completion of the last therapy.