The modulatory role of sulfated and non-sulfated small molecule heparan sulfate-glycomimetics in endothelial dysfunction: absolute structural clarification, molecular docking and simulated dynamics, SAR analyses and ADMET studies† † Electronic supplementary information (ESI) available: Compound characterisation, 1H and 13C NMR spectra, docking studies, crystallographic data for 22 and biological assays. CCDC 2038360. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/d0md00366b