inflamatuvar barsak hastalığı olan hastalarda tiroid hormonları ve otoantikorlarının değerlendirilmesi

Background and Aims: Inflammatory bowel diseases are diseases with unknown pathogenesis, and many concomitant extraintestinal manifestations can be seen. One of the concomitant diseases is autoimmune thyroid disease. The aim of our study was to evaluate thyroid hormones and autoantibody levels in Crohnas disease and ulcerative colitis. Materials and Methods: Inflammatory bowel diseases patients who applied to the outpatient clinic were evaluated for thyroid stimulating hormone, FT3, FT4, anti-thyroid peroxidase and antithyroglobulin. Results: A total of 155 patients (119 ulcerative colitis and 36 Crohnas disease) were enrolled into the study. Autoantibodies were detected in 23 patients (19.3%) with ulcerative colitis and 4 patients (11.1%) with Crohnas disease. Subclinical hypothyroidism was found in 3 patients with ulcerative colitis. Subclinical hyperthyroidism was found in 7 patients with ulcerative colitis and 1 patient with Crohnas disease. No new cases of hypothyroidism or hyperthyroidism were found except 1 ulcerative colitis patient and 1 Crohnas disease patient, who were previously diagnosed as hypothyroid. No difference was found between these two diseases regarding autoantibodies and thyroid diseases. Conclusions: Although no increase in the rate of hypothyroidism or hyperthyroidism was found, the high rate of autoantibodies detected suggests that inflammatory bowel diseases and thyroid disease can be found together. Further studies are required.