ent-Kaurane and beyerane diterpenoids from Excoecaria agallocha.

The roots of Excoecaria agallocha yielded four new diterpenoids, ent-3β,20-epoxy-3α,6α-dihydroxykaur-16-ene (agallochin F) (1), 3β,20-epoxy-3α-hydroxybeyer-15-ene (agallochin G) (2), 3β,20:15R,16S-diepoxy-3α-beyeranol (agallochin H) (3), and 3β,20-epoxy-3α,6α-dihydroxy-18-nor-beyer-15-ene (agallochin I) (4), along with three known derivatives, 2-acetoxy-1,15-beyeradiene-3,12-dione (5), 2-hydroxy-1,15-beyeradiene-3,12-dione (6), and ent-kauran-16β-ol-3-one. The structures of 1−4 were determined by spectroscopic (NMR and MS) data interpretation.