Identification of hub ubiquitin ligase genes affecting Alzheimer's disease by analyzing transcriptome data from multiple brain regions.

Dahai Liu,Shao-Xing Dai,Kan He,Gong-Hua Li,Justin Liu,Leyna G Liu,Jing-Fei Huang,Lin Xu,Wen-Xing Li

Identification of hub ubiquitin ligase genes affecting Alzheimer's disease by analyzing transcriptome data from multiple brain regions.

2021

Dahai Liu
Shao-Xing Dai
Kan He
Gong-Hua Li
Justin Liu
Leyna G Liu
Jing-Fei Huang
Lin Xu
Wen-Xing Li

The ubiquitin-proteasome system (UPS) plays crucial roles in numerous cellular functions. Dysfunction of the UPS shows certain correlations with the pathological changes in Alzheimer’s disease (AD)...

Keywords:

Biology
Computational biology
Gene
Proteasome
cellular functions
Identification (biology)
Transcriptome
Disease
Gene expression
Ubiquitin ligase

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