Sentinel Node Biopsy for Melanoma. Analysis of our Experience (125 Patients)

Abstract Introduction The objective of this study is to analyze our experience in the use of sentinel node biopsy (SNB) in melanoma and identify the predictive factors of positive SNB and multiple drainage. Materials and methods Retrospective study of patients who underwent SNB for melanoma between August of 2000 and February of 2013. Results SNB was performed in 125 patients with a median of age of 55.6 (± 15) years. The anatomic distribution was: 44 (35.2%) in legs, 24 (19.2%) in arms, 53 (42.4%) trunk and 3 (2.4%) in head and neck. The median Breslow index was 1.81 (0.45–5). Between 1 and 6 nodes were isolated. The drainage was unique in 98 (78.4%) and multiple in 27 (21.6%). The trunk was the localization of 25 (92.6%) nodes with multiple drainage. The definitive result of sentinel node (SN) was positive in 18 cases (7.1%). Breslow thickness ( P =.01) was statistically significant predictor of a positive SNB. Conclusions The SNB allows patients to be selected for lymphadenectomy. Melanoma of the trunk was the principal location of multiple drainage predictors. The only predictive factor of positive SNB was Breslow thickness.