Determination of Titanium(IV) as an Additive in Organic Matrices by Reversed-Phase High-Performance Liquid Chromatography with 5,5′-Methylenedisalicylohydroxamic Acid

A reversed-phase liquid chromatographic method for the determination of titanium with 5,5'-methylenedisalicylohydroxamic acid (MEDSHA) is described. The titanium(IV) complex is formed in a MeOH-5 × 10 -3 M H 2 SO 4 medium and injected onto a Polyspher RP18 column for chromatography. The mobile phase is H 2 SO 4 (5 × 10 -3M):MeOH (4:96, v/v) and contains 1.5 × 10-3 MEDSHA. The detection limit for titanium by the proposed method is 18 μg/L. Titanium is determined in two different samples with satisfactory accuracy and precision.