Abstract WP208: Elevated Troponin Levels in Ischemic Stroke is Independently Associated With Cardioembolism

Background: Elevated cardiac troponin is a marker of cardiac disease and has been recently shown to be associated with embolic stroke risk in the general population. In the acute stroke setting, we hypothesize that elevated troponin levels are more prevalent in patients with embolic stroke subtypes [cardioembolic (CE) and embolic stroke of unknown source (ESUS)] as opposed to known non cardioembolic subtypes (NE) (large vessel disease, small vessel disease, and other). Methods: We abstracted data from our prospective stroke database and included all patients with ischemic stroke over a 22 month period. We defined positive troponin as ≥ 0.1 ng/mL. Patients diagnosed with acute myocardial infarction were excluded (n = 3).We compared clinical, laboratory and echocardiographic findings, and stroke subtypes using ESUS criteria between the two groups: Troponin+ and Troponin-. Results: We identified 1231 patients; 1129 had troponin levels available and 10.0% (113/1129) were trop+. On univariate analyses, Troponi...