Intermediate Follow-Up and Management of Previously Reported Malignant Peripheral Nerve Sheath Tumor of the Penis
2019
Abstract Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that arise from peripheral nerve fibers and primarily occur in the setting of neurofibromatosis (NF1). MPNST arising from the penis is very rare and may require mutilating surgery to achieve surgical cure. We previously reported a case of MPSNT involving the penis in a 14-month old boy treated with neoadjuvant chemotherapy, total penectomy and adjuvant radiation. Here we report intermediate follow-up of the same patient, describe his subsequent genitourinary reconstruction, and discuss management dilemmas that arise following treatment of penile MPNST.
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