Opposite alterations of endothelin-1 in lung and pulmonary artery mirror gene expression of bone morphogenetic protein receptor 2 in experimental pulmonary hypertension

Jana Veteskova,Z. Kmecova,E. Malikova,Gabriel Doka,M. Radik,Peter Vavrinec,Peter Krenek,Jan Klimas

Opposite alterations of endothelin-1 in lung and pulmonary artery mirror gene expression of bone morphogenetic protein receptor 2 in experimental pulmonary hypertension

2019

Jana Veteskova
Z. Kmecova
E. Malikova
Gabriel Doka
M. Radik
Peter Vavrinec
Peter Krenek
Jan Klimas

AbstractAim of the Study: Endothelin-1 (ET-1) overexpression was suggested to play a role in pulmonary hypertension (PH). However, the roles of ET-1 in early stages of PH remain unexplored. We exam...

Keywords:

Anatomy
Gene expression
Bone morphogenetic protein receptor
Endothelin 1
Pulmonary artery
Pulmonary hypertension
Biology
Pathology
Lung
BMPR2
Tribromoethanol
Endocrinology
Internal medicine
Respiratory rate

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