Mortality and Re-Hospitalization Rates at 3-Months and at 1-Year in Diabetic Heart Failure Patients with Reduced, Mid-Range and Preserved Ejection Fraction in the Middle East

Objective We aimed to determine the mortality and re-hospitalization rates in diabetic heart failure patients with HFrEF, HFmrEF and HFpEF. Methods We analysed 5005 patients with acute heart failure (AHF) who were enrolled in Gulf CARE, a multinational registry of patients with HF. We compared the the mortality and re-hospitalization rates in diabetic heart failure patients with HFrEF, HFmrEF and HFpEF. Results A total of 2258 (45%) AHF patients had type II diabetes. Adjusted 3 months and 12 months re-hospitalization rate between the groups when compared to HFrEF at 3 months {(HFmrEF - adjusted odds ratio (aOR), 0.80; 95% confidence interval (CI): [0.60-1.09] p=0.159)}, {(HFpEF aOR 0.78; 95% CI: [0.56-1.08] p=0.135)} and for 12 months {(HFmrEF aOR, 0.99; 95% CI: [0.74-1.33] p=0.948)}, {(HFpEF aOR, 1.05; 95% CI: [0.76-1.45] p=0.764)}. Adjusted 3 months mortality rate between the groups when compared to HFrEF at 3 months {(HFmrEF aOR, 0.86; 95% CI: [0.53-1.40] p=0.554)}, {(HFpEF aOR 0.54; 95% CI: [0.31-0.95] p=0.031)} and for 12 months {(HFmrEF aOR, 1.07; 95% CI: [0.71-1.60] p=0.753)}, {(HFpEF aOR, 0.89; 95% CI: [0.56-1.41] p=0.616)} Conclusion 3-months cumulative mortality was found high in diabetic HFrEF patients in the middle-east.