Analysis on the Blood F1ow, Pressure and Pulsatility of a Dual Pulsatile Extracorporeal Life Support

Previous trials for development of a pulsatile-Extracorporeal Life Support had some defects such as insufficient blood flow, high pressure at its membrane oxygenator and the high risk of blood cell damage. To solve those problems of previous pulsatile-ECLSs, we suggest dual pulsatile blood pump structure for the new pulsatile-ECLS. Two pulsatile pumps areconnected in a parallel manner and this new structure raises the inflow capacity and efficiency and it decreases the high blood pressure at membrane oxygenator. In in-vitro experiments, The Energy Equivalent Pressure Increment(EEP inc.) was 10%, and it showed that its pulsatilty was times higher than other commercial ECLS In in-vivo experiments, we had applied a new pulsatile-ECLS to 30 Kg pigs and a new pulsatile-ECLS couldsupport high blood flow and pulsatility above 2 L/min, 10% EEP inc.