Positive Somatostatin Receptor Expression Demonstrated on 68Ga-NODAGA-LM3 PET/CT in a Neuroendocrine Tumor Patient With Negative Immunohistochemical Staining: Conflict or Heterogeneity.
2021
ABSTRACT We present a case with pulmonary atypical carcinoid and multiple hepatic metastases. Immunohistochemical staining of liver biopsy sample was negative for somatostatin receptor subtype 2, but 68Ga-NODAGA-LM3 PET/CT scan revealed multiple positive lesions. The mismatch was actually caused by heterogeneous expression of somatostatin receptor in liver lesions.
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