Compare the influence of laparoscopic and open ecphyadectom on the immune function of the local peritoneal cavity

Objective:To compare the influence of laparoscopic and open ecphyadectom on the immune function of the local peritoneal cavity.Methods:Determination of the phagocytic function of neutrophils,the biological viability of TNF α produced by macrophages and the T lymphocytes subsets CD4+/CD8+ ratio of the peritoneal cavity in a group of 62 cases who underwent laparoscopic ecphyadectom and in another group of 66 cases who underwent open ecphyadectom.We used T test to compare the difference of these 4 indexes between both groups.Results:The group B and group A,The mean peak value of chemiluminescence was 98 and 102 respectively;the mean OD570 of L929 Cells was 0.183 and 0.152 respectively;and the CD4+/CD8+ ratio was 0.53 and 0.57 respectively.Except for the CD4+/CD8+ ratio,the difference of the other 3 indexes between both groups were of significance.Conclusion:Compared to laparoscopic surgery,open ecphyadectom has obvious depressive effects on the immune functions particularly cell-mediated immune function of the local peritoneal cavity.