Electrostatic Stabilization of Hydrosols of Calcium Carbonate Nanoparticles Synthesized by the Template Method

A method has been developed for the synthesis of calcium carbonate particles with the use of mesoporous silica particles as a template. Hydrosols of the synthesized CaCO3 particles are unstable with respect to aggregation at neutral pH values and coagulate to yield aggregates with submicron sizes. A procedure of electrostatic stabilization by adding an aqueous FeCl3 solution has been proposed for the preparation of aggregatively stable hydrosols. It has been shown that this procedure of stabilization leads to the peptization of the aggregates and makes it possible to obtain individual calcium carbonate nanoparticles with sizes of 50−80 nm. The obtained CaCO3 nanoparticles are porous, thereby making it possible to use their stable hydrosols in medicine.