multivalent vaccines synthetic nanocarriers

A composition comprising: a dosage form comprising: a first population of polymeric synthetic nanocarriers comprising a first set of surface antigens; a second population of polymeric synthetic nanocarriers comprising a second set of surface antigens; and a pharmaceutically acceptable excipient; wherein the first population of the synthetic nanocarriers and the second population of synthetic nanocarriers are combined in the dosage form to form a multivalent vaccine for administration and wherein the first set of surface antigens and the second set of surface antigens are structurally and immunologically different.