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Crystal structures of human MEK1 with carboxamide-based allosteric inhibitor XL518 (GDC-0973), or related analogs.
Crystal structures of human MEK1 with carboxamide-based allosteric inhibitor XL518 (GDC-0973), or related analogs.
2012
Kenneth D. Rice
N. Aay
Neel Kumar Anand
Charles M. Blazey
Owen Joseph Bowles
Joerg Bussenius
Simona Costanzo
Jeffry Kimo Curtis
Steven Charles Defina
Larisa Dubenko
Stefan Engst
Anagha Abhijit Joshi
Abigail R. Kennedy
Angie I. Kim
Elena S. Koltun
Julie Lougheed
Jean-Claire Limun Manalo
J.F. Martini
John M. Nuss
Csaba J. Peto
Tsze H. Tsang
Peiwen Yu
Stuart Johnston
Keywords:
Stereochemistry
Crystal structure
Allosteric regulation
Carboxamide
Chemistry
Correction
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