Small practice effects on neurocognitive testing – markers of early cognitive impairment among adolescents with SLE?

Methods TNPB, Ped-ANAM, quality of life (PedsQL), and depression scales (CDI-S) were administered by psychology associates blinded to clinical status at two research visits. Differences in mean TNPB standardized scores, PedANAM throughput scores (raw Throughput=correct responses/minute), and clinical variables between visits were compared using paired Student t-tests. Multi-variable linear regression analysis was used to assess the influence of initial test performance, aPL/LAC status, disease duration, and cumulative prednisone dosing on composite TNPB or Ped-ANAM scores at a second visit.