Study on Sufentanil combined with target controlled infusion of propofol for hysteroscope Operation

Objective To evaluate the efficacy and safetv of Sufentanil combined wiIh target controlled infusion of propofol for hysteroscope operation.Methods 60 patients of ASA Ⅰ～Ⅱundergoing Hysteroscope operation were randomly divided into three,groups.In group S,patients were anesthetized with Sufentanil(0.1ug/kg)and target controlled infusion of Propofol(3 ug/ml),in group F,patients were anesthetized with fentanyl(lug/kg)and target controlled infusion of Propofol(3 ug/ml),in group P,patients were anesthetized with target controlled infusion of Propofol(5 ug/ml).HR,MAP,SpO2,were continuously monitored.The dosage of Propofol,limb movements,waking time,orientation recovery time were recorded.Results MAP and HR were significantly higher in group P than the rest during intraoperative period(P＜0.05).The dosage of Propofol and the incidence of limb movements was reduced in group S and group F(P＜0.05)The waking time was(3.2±1.6)min,(4.8±1.3)min,(5.0±1.8)min in group S,group Fand group P'respectively(P＜0.05).The orientation reovery time Was(4.1±1.5)min,(5.9±3.2)min,(7.6 4-2.2)min in group S.group F and group P,respectively(P＜O.05).Conduaitm Sufentanil combined with target controlled infusion of propofol could offer a good sedation/analgesia during hysteroscope operation without significant side effects. Key words: Sufentanil; Propofol; Target Controlled infusion; Hysteroscope operation