Study Of Pathogenicity Of Campylobacter Using Animal Models

Enteroinvasive study of Campylobacter species was done by Sereny Test and embryonated egg inoculation. Enterotoxicity was test by rabbit ileal loop method. 12 strains of Campylobacter jejuni and 12 strains of Campylobacter coli were tested. None were positive for enteroinvasive study by Sereny test whereas 5 strains of Campylobacter showed enteroinvasive nature by egg inoculation. Rabbit ileal loop study showed only 5 were positive (8%). Animal model does not seem to be a suitable medium for testing pathogenicity of Campylobacter.