The clinical use of large dose Ambroxol in old patient undergoing abdominal operation

Objective To investigate the application value of high-dose Ambroxol in old patients after abdominal surgery.Methods 60 cases of the old patients after abdominal surgery were randomly divided into two groups.The observation group(n =30) with continuous intravenous infusion of high-dose Ambroxol;the control group(n =30) with continuous intravenous infusion of conventional doses Ambroxol.The level of PaO2,PaCO2,TCO2,expectoration,the incidence of pulmonary infection and the pulmonary atelectasis were analyzed.Results The level of PaO2,PaCO2,TCO2 in the observation group were significantly superior to that of the control group(P0.05).Large dose of Ambroxol by intravenous drip could cause the sputum in lung easy to become thin,cough up and be aspirated.The infection of lung infection in the treatment was significantly lower than that of the control group,but the incidence of the pulmonary atelectasis was the same of the two groups.Conclusion The large dose mucosolvan applied to the perioperative period of the upper abdominal operation are safe and effective,suggesting should popularized in the clinical application.