Postoperative Recurrence Factors of Spinal Tuberculosis COX Regression Analysis

Objective: To study postoperative recurrence of spinal tuberculosis risk factors and the relative degree of risk.As far as possible to avoid the oc currence of recurrence and improve the cure rate of surgical treatment of Tuberculous spondylitis.Methods: There were clinical data,257 cases of spinal tuberculosis in patients during January 2000 ~ August 2008,which was applied to COX proportional hazards regression model,to analyse postoperative recurrence time and the 9 related factors and risk including: age,sex,self-nutritional condition,complicated spinal lesion,range of lesion,debridement of lesion,pre-operative and post-operative regular chemotherapy,surgical method(debridement or / with bone graft and anterior debridement bone grafting and internal fixation).Results: Multivariate Cox regression analysis showed that postoperative anti-TB treatment time(RR = 0.086,P = 0.016),debridement of lesion(RR = 24.121,P = 0.003) and surgical method(RR = 0.074,P = 0.037) three factors and the recurrence of spinal tuberculosis have similar correlation,after 1 ~ 2 years,overall cumulative recurrence rates were 7%.Conclusions: Postoperative regular anti-TB treatment,surgery for the elimination of lesions and anterior debridement and internal fixation can reduce the recurrence of spinal tuberculosis.Of relapse after 1 ~ 3 years when the centralized time.